Biology
Scientific milestones to commercial maturity

Biology
Industries
Biology companies often move faster scientifically than organisationally. A platform proves itself, the trial advances and the manufacturing route becomes possible. The company earns more attention from investors, partners, customers or regulators. But the next stage usually asks a different question.
— Biotechnology
— Life sciences
— Synthetic biology
— Lab innovation
— Diagnostics
— Pharma
— Research-driven companies
— Industrial biotech
— AgBio
— Others
Can the company turn that scientific progress into a capital story, a launch model, a supply chain, a market position and an organisation that can carry it?

We work with leadership teams at the point where that gap starts to widen: when the technology has earned the opportunity, but the company around it needs to become sharper, more legible and more commercially ready.

Three patterns shaping Biology

''Biology companies reach maturity when scientific progress becomes legible as capital strategy, market focus and organisational readiness.''
Soufyan Lamdini
Strategist
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The conditions around biology and life sciences have changed. The market is not simply rewarding promise, novelty or technical depth. It is asking whether a company can finance the next milestone, reach the market after approval, and build supply that can repeat.

Those questions show up differently across biotech, diagnostics, pharma services, industrial biotech and AgBio. But underneath them is the same pattern: scientific progress is no longer enough on its own. The company has to become commercially, operationally and financially credible at the same time.
01. Capital has gone selective
The broad platform story is harder to fund than it was. Investors are looking for clearer milestones, more disciplined sequencing and a more credible path from scientific progress to value creation. EY’s Biotech Beyond Borders 2025 reported that 39% of biotechs assessed in 2024 had less than twelve months of cash on hand, the highest level in at least six years.

That changes the financing narrative. Companies raising successfully are not just explaining what the science could become. They are showing which milestone matters next, why that milestone is defensible, what it unlocks, and how the organisation is built to reach it without losing focus. For leadership teams, the work is no longer only to tell a compelling scientific story. It is to turn that story into a sequence the capital market can believe.
02. Approval is no longer the finish line
For many life-sciences companies, approval used to be the obvious point of arrival. Now it is more often the beginning of a different problem. A product can clear a regulatory hurdle and still struggle to become reimbursed, prescribed, procured or embedded in clinical practice. McKinsey has found that only 20 to 30% of first-time biotech launchers exceed launch expectations, compared with 40 to 50% for established players.

That gap matters because many biology companies are approaching the market without the commercial infrastructure of a larger pharmaceutical company. In Europe, the EU Joint Clinical Assessment process adds another layer of evidence pressure. Since January 2025, new oncology medicines and advanced therapy medicinal products have been subject to joint clinical assessments, making it even more important to prepare evidence that can travel across regulators, payers and health systems.

The work that decides launch success therefore starts long before launch. It sits in market access, evidence planning, clinical workflow, pricing, reimbursement, stakeholder education and the basic question of who needs to believe what before adoption can happen.
03. From first-of-a-kind to Nth-of-a-kind
In industrial biotech, synthetic biology, biomanufacturing and AgBio, the challenge often shifts from proving that something can work once to proving that it can work repeatedly. A first plant, pilot line or flagship customer can create momentum. But it does not automatically create a bankable, repeatable model. The harder question is whether the company can move from a first-of-a-kind asset to a second, third and fourth deployment without rebuilding the business case each time.

That is where supply-side execution becomes decisive. Manufacturing strategy, licensing, project finance, offtake quality, site selection, feedstock access, regulatory exposure and geopolitical resilience all start to affect enterprise value. For many companies, the question is not whether the biology works. It is whether the operating model around the biology can scale without consuming too much equity, time or organisational bandwidth.

The companies that move through this phase well are usually the ones that become more disciplined earlier. They know what should be owned, what should be partnered, what should be licensed, and what kind of capacity actually matches the market they are trying to build.
The science moves first, and the capital follows. A trial advances, a plant is built, a launch approaches and a partnership becomes possible. And then the company finds itself playing two games at once: still being a science company, while also becoming a commercial one.

Most of the energy stays with the first. The second is often built in fragments. From the outside, that can still look coherent. From the inside, the operating reality starts to drift. The financing story lives with the CFO. The launch risk sits with commercial. The supply question sits with operations. The evidence plan sits with regulatory or medical. The website says one thing. The board pack says another. The market reads one company.

The work is to make it one again. To rebuild the layer between the science and the market as a single piece: capital story, commercial model, launch preparation, supply strategy, positioning and organisational design. Not as separate workstreams, but as one company becoming ready for the next stage.

This is the layer we work on. With leadership, alongside the people already running the company. The first conversation is usually less about a programme and more about understanding where the company is starting to drift: between science and capital, approval and adoption, first proof and repeatable scale.
Where the work happens

Interconnectivity: Biotech
A longer read on what’s shaping the sector

The Interconnectivity Series
Drawing Cross-Industries Learnings

Some of the thinking behind that work is in Interconnectivity: Biotech. A longer read on the structural shifts underneath the announcements, the patterns we are watching, and where the sector is going next.
Other industries

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